5-HTP (5-Hydroxytryptophan), Pure Encapsulations Enhances brain serotonin 5-Hydroxytryptophan (5-HTP) is an intermediate in the natural synthesis of the essential amino acid, tryptophan, to serotonin. In clinical studies, administration of 5-HTP increased serotonin levels. The enzyme tryptophan hydroxylase adds a hydroxyl group (OH) to tryptophan, forming the 5-HTP intermediate. In the body, it converts to serotonin with the removal of a carboxyl group (COOH) by a second enzyme. The 5-HTP supplied in this supplement is derived from the Griffonia simplicifolia plant. Serotonin is an important neurotransmitter involved in the regulation of endocrine and brain activity responsible for emotion, appetite and sleep/wake cycles. Supplementation with 5-HTP encourages brain serotonin levels that can lead to positive effects on emotional well-being, appetite control, and wake/sleep cycles. Suggested Use 1 to 3 capsules per day, in divided doses, before meals. Note Not to be taken by pregnant or lactating women. Do not use concurrently with SSRI medications or MAO inhibitors.  Supplement Facts   Container Size 180 Caps   Serving Size 1 Vegi Cap   Amount Per 1 Vegi Cap Content %DV     5-hydroxytryptophan (Griffonia simplicifolia) (hypo-allergenic plant fiber added to complete capsule volume requirement) 100 mg   % Daily Values (DV) are based on a 2,000 calorie diet. * Daily Value (DV) not established. Product: 5-HTP (5-Hydroxytryptophan) Manufacturer: Pure Encapsulations Item #: HYD11 Content: 180 Caps