EstroFactors, Metagenics Targeted Nutritional Support for Healthy Hormone Balance EstroFactors promotes healthy hormone balance in women of all ages by featuring targeted nutrients that support healthy estrogen metabolism and detoxification. Supporting a healthy balance of hormones may provide significant relief for women with hormone-related health issues, and may result in improvement in symptoms of premenstrual syndrome, perimenopause, and menopause. Supports women with estrogen-related health issues by addressing multiple factors of estrogen activity and metabolism. Promotes healthy estrogen detoxification and elimination from the body, thus supporting overall hormone balance. Helps to modulate pathways of estrogen metabolism, such as the conversion of estradiol to 2-hydroxyestrone, a weaker estrogen that may protect estrogen-sensitive tissues. Beneficially influences estrogen receptor function for more balanced estrogenic activity. Features ActiFolate®, a proprietary blend of active folates that includes 5-formyl tetrahydrofolate, L-5-methyl tetrahydrofolate, and folic acid for greater bioavailability. Recommendations: Three tablets daily with a meal. Warning: If pregnant or nursing, or taking medication, consult your healthcare practitioner before use. This product has not been tested for interactions with oral contraceptive medications, and the effectiveness of oral contraceptives for birth control cannot be ensured during use of EstroFactors. Vitamin A Warning: Excess Vitamin A intake may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 5,000 IU of pre-formed vitamin A (retinyl acetate or retinyl palmitate) per day. It is also recommended that children under four should not regularly consume more than 2,500 IU per day.      Supplement Facts   Container Size 180 Tabs   Serving Size 3 Tabs   Amount Per 3 Tabs Content %DV     Vitamin A (50% as Betatene® mixed carotenoids and 50% as retinyl palmitate) 2500 IU   Vitamin D (as cholecalciferol) 200 IU   Vitamin E (as d-alpha tocopheryl acetate) 200 IU   Vitamin K 40 mcg   Vitamin B6 (as pyridoxine hydrochloride) 50 mg   Folate† (as L-5-methyl tetrahydrofolate††, folic acid, and 5-formyl tetrahydrofolate) 800 mcg   Vitamin B12 (as methylcobalamin and cyanocobalamin) 30 mcg   Trimethylglycine 200 mg   Chrysin 90 mg   Isoflavones [from a proprietary blend of Red Clover Flowering Top extract (Trifolium pratense) and Kudzu Root Extract (Pueraria lobata)] 100 mg   Turmeric Rhizome Extract (Curcuma longa) [standardized to 95% (200 mg) curcuminoids] 210 mg   Rosemary Leaf Extract (Rosmarinus officinalis) [contains 5.1%-7.6% (10.2 mg-15.2 mg) carnosic acid/carnosol] 200 mg   Resveratrol (from Polygonum cuspidatum root extract) 2 mg     † Featuring ActiFolate®, a proprietary blend of active folates. †† As Metafolin® U.S. Patent Nos. 5,997,915; 6,254,904. Patent Pending   % Daily Values (DV) are based on a 2,000 calorie diet. * Daily Value (DV) not established. Product: EstroFactors Manufacturer: Metagenics Item #: ESTRFAC180 Content: 180 Tabs