 |  Product Name: UBQH 50mg
Manufacturer: Integrative Therapeutics
Item #: 770026
Content: 60 Softgels
More Details
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 Patented stabilized reduced ubiquinol. Enhanced bioavailability - 62% higher than CoQ10.
Although CoQ10 is produced by the body and exists in some dietary sources, these levels may be
insufficient to meet the body's requirements. Additionally, a deficiency can result from increasing
age or increased tissue demands. However, supplementing with CoQ10 may not be enough: approximately
30-50% of humans have a genetic make-up (NQ01 or NAD(P)H:quinbne oxicloreductase 1) that inhibits
the conversion of CoQ10 (ubiquinone) to its active and reduced form of QH (ubiquinol), further
depleting levels below what is required to support cellular energy and promote overall health.*
Ubiquinone (Coenzyme 010, CoQ10) and Ubiquinol (QH) are closely related compounds naturally
occurring in the human body. CoQ10 is converted to its active form, QH, as a necessary and essential step
in the production of cellular energy. The conversion rate of CoQ10 to QH tends to decline with age,
resulting in lower serum of QH.' A genetic trait in the human population has also been linked to impaired
ability to conduct this conversion!
QH outside the body is an extremely unstable compound, converting to CoQ10 upon exposure to oxygen. New
research has led to the development of a method to stabilize QH while protecting it from oxygen.' UBQH
contains this patent pending, stabilized, active ubiquinol, which has been shown to have greater bioactivity
than CoQ10.*
For those who are older, those requiring higher doses of CoQ10 or those with the genetic
SNP associated with decreased CoQ10 redox ratios, recommend UBQH-the only patented, stable and
proven -effective QH solution available.*
UBQH Features
- Exclusive, patented form of ubiquinol
- Efficient delivery system especially important for individuals requiring high dose CoQ10
- Demonstrated to increase plasma levels of total CoQ10 up to 62% higher than traditional CoQ10 supplementation
- Patented processing method prevents oxidation and ensures a stable product
- No significant adverse effects reported during safety and toxicological studies
SCIENTIFIC RESEARCH: Studies have shown that supplemental QH may have the same health benefits as CoQ10, in
a more active form - one step in the conversion process of CoQ10 to QH is eliminated. Scientific studies of
QH have additionally found that it provides support for healthy aging, and increases stamina and energy.*'
In an evaluation of energy (calculated as time to fatigue) in an animal model, older animals received
placebo, CoQ10, and QH in crossover design. Running times were measured in each group. When the animals
received QH running times were prolonged 150 fold versus placebo. Increases during the CoQ10
supplementation period did not reach statistical significance.*9
In an experiment which used an animal model of aging, QH supplementation was associated with healthier
aging (as determined by skin, eye, skeletal and general health) in comparison to aging in the both the
CoQ10 and control group.*10 The control group in this experiment experienced double the senescence
scores in midlife when compared to the QH group, while the CoQ10 supplemented group had senescence
scores approximately 1.5 times as high as the QH group.* Increased senescence scores are an indication
of the signs of aging.
Bioavailability studies in humans are ongoing. The amount of plasma and brain levels CoQ10 increase
compared with oral CoQ10 is variable, and based on age and genetics. However, results to date have
found that intake of active QH is associated with total serum CoQ10 (ubiquinone plus ubiquinol) levels
at least 2 times higher than oxidized CoQ10.
SAFETY: The safety of QH has been extensively studied. Acute toxicity and short term safety studies
found no significant adverse effects. Genotoxicity tests, including Ames, chromosome and micronucleus
tests, were all negative.
STABILITY: As previously noted, QH outside of the body is not stable, and quickly converts back to
CoQ10 in the presence of oxygen. Therefore, its potential use as an oral supplement has been limited.
A patented process to prevent QH from oxidizing has now been developed' UBQH features this stabilized
form of ubiquinol, in an exclusive softgel capsule. This product remains shelf-stable to deliver potent
QH, and has been demonstrated to significantly raise serum levels of CoQ10.
CONCLUSION: UBQH is a stabilized ubiquienol product. Providing unique support for energy production
and healthy aging, supplemental ubiquinol may be a more appropriate supplement choice for older
adults, those requiring higher doses of CoQ10 or those with the genetic SNIP associated with
decreased CoQ10 redox ratios.
For those who are older, who test positive for NQO1, or require substantial CoQ10 supplementation
for neurological health, recommend UBQH-the only patented, stable and proven-effective QH solution available.
Store at room temperature (25° C or 77° F) in an airtight container and away from light. Use
immediately upon opening.
ITI evidence-based medicines are the only choice of doctors who rely on the fact base of premier science
to deliver patient results.
See chart on outer box for Plasma Concentration.
Recommendations:
One softgel with a glass of water, twice daily.
| Supplement Facts (UBQH 50mg) | |
Container Size 60 Softgels | | Serving Size 1 Softgel |  | | | Amount Per 1 Softgel | Content | %DV | | | | | | Calories | 5 | | | | Calories from fat | 5 | | | | Total Fat | 0.5 g | < 1 % | | | Reduced Form Coenzyme Q10 (as ubiquinol) (Kaneka QH™) | 50 mg | * | | | | | | Other Ingredients: canola oil, gelatin, diglyceryl monooleate (soy), vegetable glycerin, beeswax, caramel color, and soy lecithin | | | Contains No: salt, yeast, wheat, gluten, corn, dairy products, artificial flavoring or preservatives. All colors used are from natural sources | | | | % Daily Values (DV) are based on a 2,000 calorie diet.
* Daily Value (DV) not established. |
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