Perfusia-SR, Thorne Research

Product Name: Perfusia-SR

Manufacturer: Thorne Research
Item #: SA525
Content: 120 VegiCaps

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sustained-release L-arginine - the most important cardiovascular product of the decade*

when sufficient L-arginine is present:

arteries relax, promoting optimal blood flow*
as arteries relax, already normal blood pressure can be better maintained*
erections occur in the normal course of intimacy*
supple, flexible arteries are better able to support good cardiovascular health*

Product Information
Sustained-release L-arginine supports cardiovascular function, wound healing, and immune function* – and is a biological precursor to nitric oxide*

L-arginine is a semi-essential amino acid involved in multiple areas of human physiology and metabolism. L-arginine significantly affects endocrine function and helps regulate the release of neurotransmitter chemicals, insulin, glucagon (which has the opposite effect of insulin; i.e., it raises blood sugar), and growth hormone.* However, one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide.* The vascular endothelium (lining of the arteries) creates nitric oxide from L-arginine, resulting primarily in blood vessel relaxation.* This property is critical to maintaining good vascular health, heart health, reproductive health, and protection against oxidative damage.*

Maintaining the natural, healthy functions of the vascular endothelium is dependent upon an adequate supply of L-arginine being available to these cells.* As mentioned above, the conversion of L-arginine to nitric oxide is responsible for these functions by making the endothelial cells more resistant to oxidative damage and adhesion by otherwise harmful substances.* Numerous studies have demonstrated that individuals with sufficient nitric oxide production by endothelial cells have the best opportunity to maintain already normal cardiovascular health.*

In a large, double-blind trial that observed male reproductive health issues, 1.6 g L-arginine daily for six weeks resulted in improvement in reproductive health in those men with low nitric oxide metabolism.*

Like most amino acids, L-arginine functions as a building block of proteins; however, its presence also appears to support wound healing.* Numerous studies show L-arginine supplementation benefits wound healing time and strength of the tissue in and around the wound during the healing phase.*

Without adequate L-arginine (and subsequently, nitric oxide) available to vascular endothelial cells, arteries may not optimally dilate, which can result in less than optimal blood flow to the organs and extremities.*

L-arginine is absorbed and metabolized by the body very quickly, which usually necessitates taking it frequently throughout the day. Sustained-release Perfusia-SR, however, maintains an optimal level of L-arginine over 24 hours with suggested twice-daily use.*

Studies on Perfusia-SR show increased blood flow to the heart muscle and the extremities, maintenance of already normal blood pressure, and improved vascular elasticity.* A recent study demonstrated improvements in blood flow after Perfusia-SR supplementation in individuals with less than optimum heart health.* In another study, Perfusia-SR was given to 29 healthy volunteers for one week and significant support for healthy cardiovascular system was observed.*

Suggested Use:
Take 2 capsules two times daily or as recommended by your health-care practitioner.

INTERACTIONS/CONTRAINDICATIONS
Individuals with a known herpes infection should not take L-arginine without also taking lysine, as L-arginine alone has been noted to cause herpes eruptions in susceptible individuals. L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.

Supplement Facts (Perfusia-SR)
Container Size 120 VegiCaps
Serving Size 2 VegiCaps

	Amount Per 2 VegiCaps	Content	%DV

	L-Arginine*	1 g

	Other Ingredients: High and low viscosity hydroxypropyl methylcellulose and MagnesiumCitrateLaurate (Time-Sorb), Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. L-Arginine complexed with Time-Sorb®, a time-release matrix.

	% Daily Values (DV) are based on a 2,000 calorie diet. * Daily Value (DV) not established.