T.A.P.S., Thorne Research

Product Name: T.A.P.S.

Manufacturer: Thorne Research
Item #: SF773
Content: 60 VegiCaps

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superior hepatoprotective herbal formula with flavonoid phytosomes for enhanced absorption*

with Siliphos® (silybin phytosome) and Meriva® (curcumin phytosome) for better absorption*
picrorhiza protects liver cells from the effects of toxic compounds*

Product Information
Silybum marianum (milk thistle) has been used for centuries to support liver function.* Silymarin's hepatoprotective effects are accomplished via several mechanisms, including antioxidation, inhibition of lipid peroxidation, enhanced liver detoxification via inhibition of phase I detoxification and enhanced glucuronidation, and protection of glutathione depletion.* Siliphos consists of the most potent flavonoid in silymarin (silybin) bound to phosphatidylcholine for enhanced hepatoprotection and bioavailability.*

Curcumin, an active flavonoid from turmeric, has potent antioxidant, hepatoprotective, and gastroprotective properties.* Curcumin is bound to phosphatidylcholine in the highly bioavailable phytosome complex – Meriva.* Cynara scolymus (artichoke) has a long history of use in hepatic support.*

Picrorhiza is used in Ayurvedic medicine to optimize liver function.* In studies, Picrorhiza extracts and their constituents protected liver cells from damage caused by carbon tetrachloride, aflatoxin B1, and acetaminophen.* Picrorhiza acts as an antioxidant and inhibitor of lipid peroxidation in cell membranes, and it also increases bile flow.* The hepatoprotective effects of Picrorhiza may be due to its antioxidant activity – inhibition of oxygen anion generation and free-radical scavenging.* Like silymarin, Picrorhiza can stimulate liver regeneration, possibly via stimulation of nucleic acid and protein synthesis.*

Suggested Use:
Take 1 capsule two to three times daily or as recommended by a health-care practitioner.

INTERACTIONS/CONTRAINDICATIONS
Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research reveals curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.

Supplement Facts (T.A.P.S.)
Container Size 60 VegiCaps
Serving Size 1 VegiCap

	Amount Per 1 VegiCap	Content	%DV

	Artichoke extract (leaf) (Cynara scolymus)	125 mg
	Curcumin Phytosome* (Curcuma longa extract (root) / Phosphatidylcholine complex)	125 mg
	Picrorhiza extract (root) (Picrorhiza kurrooa)	125 mg
	Silybin Phytosome* (Silybum marianum extract (seed) / Phosphatidylcholine complex)	125 mg

	Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. *This product uses Indena S.p.A.'s curcumin phytosome (Meriva®) and silybin phytosome (Siliphos®). Meriva and Siliphos are registered trademarks of Indena S.p.A. Cynara PE 4:1. Picrorhiza standardized to Kutkin 4%. Contains ingredients derived from soy (phytosomes).

	% Daily Values (DV) are based on a 2,000 calorie diet. * Daily Value (DV) not established.