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Product Detail: Ribose, Pure Encapsulations
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Rapid energy repletion for intense exercise
Over 150 studies demonstrate the ability of ribose, a pentose sugar found in all living cells, to increase adenosine triphosphate (ATP) levels and total adenine nucleotide (TAN) recovery, promoting skeletal and cardiac muscle energy metabolism. Ribose is the key compound used by the body to form the nucleotides AMP, ADP and ATP, which are depleted during strenuous physical activity or from lack of oxygen. Skeletal and cardiac muscle rely on these metabolites for energy, and two metabolic pathways preserve these pools. The first mechanism involves salvaging end products of AMP breakdown, or preventing them from leaving the cell. If they are salvaged, they may be recycled back to AMP and ultimately to ATP
The second mechanism for preserving nucleotide pools is de novo synthesis, or formation of new nucleotides from ribose. Both of these crucial activities can only begin when ribose is converted to 5-phosphoribosyl-1-pyrophosphate (PRPP). If ribose concentrations are not sufficient, PRPP is in low supply and muscle cells cannot adequately recharge. Although the body has the ability to manufacture ribose from glucose, it is a slow process which requires glucose-6-phosphate dehydrogenase (G- 6-PDH), an enzyme typically in short supply. Supplemental ribose allows the body to bypass this step, rapidly supplying the compounds needed to boost salvage and enhance de novo synthesis.
Research indicates that nucleotides decrease after repeated, intense exercise and that they may not be recovered for up to several days, leaving muscle without the ability to refuel energy stores. Ribose also offers powerful, complementary support to creatine by enhancing TAN pools, providing the necessary substrates which creatine can then convert to ATP.
Ribose, taken before, during or after high-intensity exercise, accelerates replenishment of depleted adenine nucleotide pools, keeping ATP and TAN levels at their peak, and providing rapid regeneration of critical energy molecules for maximal training.
Suggested Use 1–2 scoops per day, 30 minutes before or following an exercise session, or in divided doses before and after exercise. On days with no exercise scheduled, take in the evening before bedtime.
| Supplement Facts | |
Container Size 250 g | | Serving Size 1 Scoop |  | | | Amount Per 1 Scoop | Content | %DV | | |  | | | d-ribose
| 2.2 grams | |  | | | % Daily Values (DV) are based on a 2,000 calorie diet. * Daily Value (DV) not established. |
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Ribose, Pure Encapsulations ( Manufacturer's Sku #: RI2 )
Size: 250 g Suggested Retail Price: $79.50 Price: $79.50 (log-in for special-price)
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| - Free shipping on orders over $45; all others are shipped for a flat rate of $5.
- Sale of Pure Encapsulations products below SRP is not available due to the manufacturer's policy, however, you will be able to receive special price and additional volume discounts once you become a Registered User. (more about our price structure).
- The statements provided are for information use only and is not intended to substitute advice from your physician or health care provider. Always follow the manufacturer's recommended dosage or suggested use. If you have any special medical condition including pregnancy or nursing, consult your physician.
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