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Product Detail: Cardio-Edge, Douglas Labs
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 Scientifically-based cardiovascular and cholesterol support with Sytrinol™, plant sterols and pomegranate extract.
In human clinical studies involving hypercholesterolemic subjects; 4 weeks of supplementing with a daily dose of 300 mg. of Sytrinol™ resulted in:
Average reductions of total cholesterol by 20-24%,†Average reductions of LDL-cholesterol by 19-22%,†Average reductions of triglycerides by 24-28%,†LDL/HDL ratio was significantly improved.†
Now you can take the EDGE off their cholesterol – with new Cardio-Edge™, exclusively from Douglas Laboratories.® Douglas Laboratories is the exclusive provider of Sytrinol. Each daily dose of Cardio-Edge (2 vegetarian capsules twice daily) contains 300 mg. of Sytrinol, a patented citrus-based extract clinically proven to reduce cholesterol, as well as 800 mg. of plant sterols and 100 mg. of pomegranate extract.† There’s no other product like it!
DESCRIPTION:
Cardio-Edge continues Douglas Laboratories’ tradition of providing
unique, exclusive and scientifically substantiated products to health professionals. Cardio-Edge supplies Sytrinol (a patented combination of polymethoxylated flavones from citrus fruit and tocotrienols from palm), plant sterols, and standardized pomegranate extract to help support cardiovascular health and cholesterol metabolism.
FUNCTIONS:
Sytrinol A unique and powerful ingredient for maintaining cholesterol health.
The healthful effects of both bioflavonoids as well as tocotrienols have been recognized for
years. Sytrinol provides a patented and wellresearched combination of flavonoids
derived from the peel of tangerines and tocotrienols derived palm. Within the peel of
certain fruits, compounds belonging to a class of flavonoids called polymethoxylated
flavones can be found. These compounds are similar in structure to flavones, but contain
additional methyl groups on their ring structure, giving them the name polymethoxylated
flavones also known as PMFs.
The primary PMFs present in Sytrinol are
nobiletin and tangeretin. Science on PMFs dates back to the 1960s and covers both
their antioxidant as well as their anti-inflammatory actions. Specifically, with respect to
cholesterol metabolism, PMFs have been shown to decrease apolipoprotein B, the
structural protein needed for the synthesis of LDL-cholesterol. Nobiletin and tangeretin
have also been shown to decrease diacylglycerol acetyl transferase, an enzyme in the
liver involved in the synthesis of triglycerides. In addition to PMFs, Sytrinol contains
tocotrienols derived from palm. Tocotrienols, a group of compounds belonging to the vitamin
E family, have also been studied over the years for their ability to act as antioxidants
and to help support cardiovascular health.
Tocotrienols have been shown to inhibit
HMG-CoA reductase, the hepatic enzyme responsible for the rate limiting step in the
synthesis of cholesterol. Consequently, the combined action of the PMFs and tocotrienols
contained in Sytrinol results in a powerful synergistic action to support cardiovascular
health. This effect has been confirmed in both animal as well as human studies. In
human clinical studies, Sytrinol given at a dose of 150 mg twice daily (daily dose of
300 mg) to hypercholesterolemic subjects for 4 weeks resulted in average reductions of
total cholesterol by 20-24%, LDL-cholesterol by 19-22 %, and triglycerides by 24-28%.
Additionally, the LDL/HDL ratio was significantly improved. Larger and longer follow
up studies involving 120 hypercholesterolemic subjects supplemented for 12
weeks have yielded similar findings.
Plant Sterols
Plant sterols are naturally occurring plant compounds that have structures similar to, yet
slightly different from cholesterol. Typical plant sterols are compounds such as ß-sitosterol,
campesterol, and stigmasterol and can be found in vegetables, fruits, legumes, nuts,
grains and certain oils. Research has shown that these compounds compete with the
absorption of dietary cholesterol as well as inhibit the reabsorption of endogenous cholesterol
in the gastrointestinal tract. Supplementation with plant sterols can significantly
lower cholesterol levels and have been shown to work synergistically with other
therapies for lowering cholesterol.
Numerous foods including orange juice, rice
drink, and margarine now incorporate plant sterols, or sterol esters. Increasingly, dietary
supplements are now incorporating plant sterols and using the health claim that has
been allowed for products containing at least 800 mg of plant sterols daily. The addition of
plant sterols to Cardio-Edge provides yet another mechanism by which healthy cholesterol
levels can be maintained.
Pomegranate
Recent science has been focusing on the cardioprotective aspects of pomegranate. These
brightly colored fruits contains numerous compounds known for their antioxidant capabilities,
including anthocyanidins, catechins, tannis, and gallic and ellagic acids. Research
has shown that supplementation with pomegranate juice can decrease macrophage lipid
accumulation, and cellular cholesterol accumulation in mice. Recently, research in
humans has confirmed a beneficial effect of consuming pomegranate juice on parameters
such as LDL oxidation, blood pressure, and blood vessel health.The combination of
Sytrinol, plant sterols, and pomegranate extract present in Cardio-Edge results in a
formula that embodies the most recent science to help maintain cardiovascular health and
support healthy cholesterol levels.
SUGGESTED USE:
Adults take 2 capsules, twice daily with meals or as directed by physician.
| Supplement Facts | |
Container Size 120 VegiCaps | | Serving Size 2 Caps |  | | | Amount Per 2 Caps | Content | %DV | | | | | | Plant Sterols (Phytosterols) | 400 mg | | | | Sytrinol
(proprietary blend of polymethoxylated flavones and
tocotrienols from citrus and palm fruits) | 150 mg | | | | Standardized Pomegranate
Extract (Fruit) (Standardized to 40% ellagic acid) | 50 mg | | | | | % Daily Values (DV) are based on a 2,000 calorie diet.
* Daily Value (DV) not established. |
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 Cardio-Edge, Douglas Labs
( Manufacturer's Sku #: 99134-120X )
Size: 120 VegiCaps
Suggested Retail Price: $40.40
Price: $40.40 (log-in for special-price)
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| - Free shipping on orders over $45; all others are shipped for a flat rate of $5.
- Special price and additional volume discounts are available for Registered Users. (more about our price structure).
- The statements provided are for information use only and is not intended to substitute advice from your physician or health care provider. Always follow the manufacturer's recommended dosage or suggested use. If you have any special medical condition including pregnancy or nursing, consult your physician.
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