 |  |
Product Detail: Sublingual-12 Plus, Douglas Labs
 |
|
 Stress control
Sublingual-12 Plus tablets, as provided by Douglas
Laboratories®, dissolve rapidly in the mouth,
releasing 1,000 mcg of pure vitamin B12 together with
400 mcg of folic acid.
FUNCTIONS
Vitamin B12 is essential for normal energy
metabolism of carbohydrate, fat and protein. As a
cofactor for methylmalonyl-CoA mutase enzymes,
vitamin B12 helps convert odd chain fatty acids and
branched chain amino acids into succinyl-CoA, a
common citric acid cycle intermediate. Vitamin B12
is also required for nucleic acid (DNA) synthesis,
methionine synthesis from cysteine, and normal
myelin synthesis in the nervous system. Along with
vitamin B6 and folic acid, adequate levels of vitamin
B12 are required to maintain normal plasma
homocysteine levels. Elevated plasma homocysteine
may be an independent risk factor for developing
cardiovascular disease.
There are two distinct mechanisms for intestinal
vitamin B12 absorption; receptor-mediated absorption
and passive diffusion. In the first, vitamin B12 attaches
to a salivary R-binder protein which transports it
into the small intestine, where vitamin B12 is released.
The vitamin then binds to Intrinsic Factor (IF), a
glycoprotein normally produced by the gastric parietal
cells. This vitamin B12-IF complex is carried down to
the ileum, where it binds to mucosal receptors.
Finally, the complex is absorbed and bound to serum
vitamin B12-binding proteins. The second absorption
mechanism, passive diffusion, does not require any
carriers, such as B-binder or IF. Only about 1% of
free vitamin B12 is passively absorbed, but this can be
nutritionally significant with higher dietary vitamin
B12 intakes.
Almost 40% of the population is suggested to have
low normal plasma B12 levels. Strict vegetarians,
the elderly, and, HIV/AIDS patients are often at risk
for vitamin B12 deficiency, either due to low dietary
intake or impaired absorption. In the elderly, hypo- or
achlorhydria maintains the binding of the vitamin
with dietary proteins, leading to malabsorption.
Vitamin B12 deficiency can lead to CNS impairment,
including cognition.
INDICATIONS
Sublingual-12 Plus tablets may be a useful dietary
supplement for individuals who wish to increase their
intake of vitamin B12 and folate.
SUGGESTED USE
Adults take 1 tablet daily or as directed by physician.
Let tablet dissolve in mouth.
SIDE EFFECTS
No adverse effects have been reported.
| Supplement Facts | |
Container Size 90 Tabs | | Serving Size 1 Tab |  | | | Amount Per 1 Tab | Content | %DV | | | | | | Vitamin B12 | 1000 mcg | | | | Folic Acid | 400 mcg | | | | | % Daily Values (DV) are based on a 2,000 calorie diet.
* Daily Value (DV) not established. |
|
|
|
 Sublingual-12 Plus, Douglas Labs
( Manufacturer's Sku #: 7560-90X )
Size: 90 Tabs
Suggested Retail Price: $9.90
Price: $9.90 (log-in for special-price)
|
| - Free shipping on orders over $45; all others are shipped for a flat rate of $5.
- Special price and additional volume discounts are available for Registered Users. (more about our price structure).
- The statements provided are for information use only and is not intended to substitute advice from your physician or health care provider. Always follow the manufacturer's recommended dosage or suggested use. If you have any special medical condition including pregnancy or nursing, consult your physician.
|
|  |  |  |
|
|
VIEW ALL PRODUCTS BY 