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Product Detail: 5-MTHF 1mg, Thorne Research
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 |  5-MTHF 1mg, Thorne Research
( Manufacturer's Sku #: B129 )
Size: 60 VegiCaps
Suggested Retail Price: $17.50
Price: $17.50
| | Free Shipping on 3 or more of this item. | |
the most biologically active form of folate*
- a breakthrough in folate supplementation
- the most bioavailable, active form of folate*
- an excellent source of folate for pregnant women*
- supports optimal cardiovascular and nerve function*
Product Information
Folic acid must be converted to its active forms to be used by the body.* This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.*
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy.* The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant.* Supplementation with the more active form may be preferable.*
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine.* Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.*
It is important for women of childbearing age to get enough folic acid – not just those who are planning to become pregnant.* Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day – especially before conception and during early pregnancy.*
Suggested Use:
Take 1 capsule one to three times daily or as recommended by a health-care practitioner.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
| Supplement Facts (5-MTHF 1mg) | |
Container Size 60 VegiCaps | | Serving Size 1 VegiCap |  | | | Amount Per 1 VegiCap | Content | %DV | | | | | | Folate (as L-5-Methyltetrahydrofolate*) | 1 mg | | | | | | | Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
*This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolate (Extrafolate-S®). Extrafolate-S is a registered trademark of Gnosis S.p.A | | | | % Daily Values (DV) are based on a 2,000 calorie diet.
* Daily Value (DV) not established. |
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- The statements provided are for information use only and is not intended to substitute advice from your physician or health care provider. Always follow the manufacturer's recommended dosage or suggested use. If you have any special medical condition including pregnancy or nursing, consult your physician.
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