Manufacturer: INTEGRATIVE THERAPEUTICS ITI is the largest provider of specialty dietary supplements to medical professionals in North America. Over 50,000 doctors recommend, prescribe and dispense our products - every day. Integrative Therapeutics Inc. (ITI) is the nation’s leading manufacturer and distributor of high quality nutritional supplements to health care practitioners and their patients. Evidence-Based Medicine Our top 50 products have been the subject of over 2,500 independent, peer-reviewed-published, double-blind, placebo-controlled clinical trials and studies. Our products are extensively used in research supported by major medical university and hospital research centers and government agencies, including the National Institutes of Health and the Veteran’s Administration. Proven and independently documented safety, efficacy and tolerability. Education Leadership We are award-winning for our branded and third-party educational materials. Our Scientific Advisory Board is comprised of over 50 medical professional experts. Larry Baskind, MD, Scott Berliner, R.Ph., James Jeffrey Bradstreet, MD, AAFP, Bruce Canvasser, ND, Donald E. Colbert, MD, Steve Cowan, MD, Carrie Louise Daenell, ND, Richard Delany, MD, FACC, Bob Doster, PhD, Shaun Dyler, ND, LAT, David Edelberg, MD, Meganne Finerty, PhD, Cynthia Frozena, MS, RN, Alan Gaby, MD, Dennis Goodman, MD, John Hahn, ND, DO, Jennifer Hansgate, MLS, Thom Hartmann, Psychotherapist, Christine Horner, MD, FACS, Frank Lipman, MD, Joel Lopez, MD, CNS, Holly Lucille, ND, RN, Allan Magaziner, DO, Zhanna Massey, MD, Jed Meese, PhD, Chris Meletis, ND, Mythili Nagarajan, MS, Pam Peeke, MD, Noel Peterson, ND, Nagmani Rangaswamy, PhD, Corey Resnick, ND, Glenn Rothfeld, MD, M.Ac., Tom Saldeen, MD, PhD, Richard Sharpee, PhD, Eileen Stretch, ND, Jacob Teitelbaum, MD, Decker Weiss, NMD We have over 40 medical-condition-expert-developed dietary supplement protocols offering clinically referenced actives, dose recommendation and condition benefits. The Working Doctor Seminar Series provides evidence-based interventions for a wide variety of health topics, presented by leading doctors in the field of complementary and alternative medicine. Drug Manufacturing Our top products are produced in an FDA-registered drug facility. We manufacture and market pharmaceuticals, OTC and dietary supplements, world-wide. Batch to batch, bottle to bottle, pill to pill, our products are consistent and as used in clinical trials. ITI is one of only a select few dietary supplement manufacturers that are in full compliance with GMPs that have already been established for drug manufacturing facilities. Currently these standards are much more complex and rigorous than those expected for dietary supplement manufacturers. ITI conducts more than 35,000 tests on its products every year. The laboratory staff is extremely knowledgeable regarding analytical methodology for botanicals and other nutrients. They have published research papers in respected peer-reviewed journals. ITI monitors and tests ingredients at various points during the manufacturing process. Before any raw material is processed, it must pass through a "quarantine" period. As part of this inspection process, ITI scientists use a variety of test methods, including High Performance Liquid Chromatography (HPLC), Atomic Absorption Spectroscopy (AA), and other chromatographic techniques, along with microbiological analysis, to ensure the purity of every ingredient. Lab analysis confirms ITI is using the correct plant and getting the right quality and quantity of chemical constituents. These analyses makes certain that bacteria have not contaminated the raw materials. Raw materials are also examined for contamination with pesticides or other toxins. Process validation studies ensure that the written process approved for each product performs consistently from batch to batch. Cleaning validation studies ensure that no residues from products, harmful microbes, or cleaning/sanitizing products remain on the equipment. ITI’s cleaning validation program was modeled after the standards maintained in drug manufacturing facilities. ITI products include ingredients derived from a variety of extraction processes, including hot water extraction, alcohol extraction and super critical CO2 extraction, to name a few. We at no time accept any raw material extracted with solvents that have shown adverse health effects. Global Responsibility Beyond using raw materials that are organic, grown without pesticides/herbicides, and are GMO-free for health standards, is the issue of sustainability for the health of the planet. Merely selecting materials that are free of chemical contamination is not necessarily supporting the wise use of the planet’s resources. Sometimes there is an overlap and sometimes, unfortunately, there is not. ITI purchases raw materials from reliable vendors who accurately monitor and report how those materials are derived. ITI does vendor spot-checks to make sure the information with which ITI is supplied is factual. ITI is cautious in use of raw materials that are from ecologically sensitive species, be they animal or plant. Organizational Support ITI supports the American Botanical Council (ABC), including providing financial support, assistance with technical information for the development of botanical monographs and safety standards. There are other organizations we support with our membership as well. The partial list includes: American Herbal Products Association (AHPA) National Nutritional Foods Association (NNFA) American Association of Naturopathic Physicians (AANP) American Botanical Association American Chemical Society Florida Chiropractic Association Oregon Association of Naturopathic Physicians Humanitarian Support Research Support ITI Brand is consisted of the following brands: NF Formulas, Inc. 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